UltraMIST® System

Select SANUWAVE's UltraMIST System as Your First Line of Defense for Advanced Wound Care

The UltraMIST System’s acoustic wave therapy promotes healing by controlling inflammation and reducing bacteria in the wound bed while increasing angiogenesis. Further promoting healing, it increases perfusion through vasodilation, ultimately increasing oxygen and nutrients to the tissue.

What can it treat?

UltraMIST Therapy has been clinically proven to promote the healing process across a wide range of chronic and acute wounds, including:

  • Venous leg ulcers
  • Diabetic foot ulcers
  • Deep tissue pressure injuries
  • Surgical wounds
  • And many more wound types
Is it painful?

UltraMIST treatment is non-contact and painless.

How long does it take?

The treatment time takes between 3-20 minutes depending upon the size of your wound.

When will I see results?

Some studies have shown reduced pain after UltraMIST Therapy is applied11, 14 and 85.2% area reduction over a mean of 7 weeks.11

Initiate Wound Healing With Noncontact, Low-Frequency Ultrasound Therapy

The UltraMIST System delivers low-frequency ultrasound to the treatment site using a noncontact fluid (e.g., saline). Administered by healthcare professionals to thousands of patients for more than a decade.

Patients reported an 80% reduction in VAS pain score over 4 weeks (vs. 20% standard of care).15

Wound closure increased to 41% with UltraMIST vs. 14.3% with standard care.6

Unlike most wound products that just treat the surface, the sound waves of UltraMIST penetrate into and below the wound to promote a normal healing process.


All typical and atypical nonhealing wounds* including but not limited to:

Diabetic Foot Ulcers5,6
Deep Tissue Pressure Injuries7-9
Venous Leg Ulcers10,11
Skin Grafts12
Chronic Wounds13,14
*Exceptions: Cancerous lesions, over-pregnant uterus, over-implanted device

Footnotes for Page

1. Noncontact low-frequency ultrasound therapy in the treatment of chronic wounds: a meta-analysis
2. UltraMIST MOA Inflammation
3. UltraMIST MOA Vasodilation
4. UltraMIST MOA Bacteria
5. A pilot study evaluating non-contact low-frequency ultrasound and underlying molecular mechanism on diabetic foot ulcers
6. Ultrasound therapy for recalcitrant diabetic foot ulcers: results of a randomized, double-blind, controlled, multicenter study
7. Effects of non contact low-frequency ultrasound on healing of suspected deep tissue injury: a retrospective analysis
8. Use of Noncontact Low-Frequency Ultrasound in Deep Tissue Pressure Injury: A Retrospective Analysis
9. Adjunctive use of noncontact low-frequency ultrasound for treatment of suspected deep tissue injury: a case series
10. A prospective pilot study of ultrasound therapy effectiveness in refractory venous leg ulcers
11. A prospective, randomized, controlled trial comparing the effects of noncontact, low-frequency ultrasound to standard care in healing venous leg ulcers
12. Noncontact Low-Frequency Ultrasound for Debridement of Necrotic Wounds to Avoid Further Surgical Intervention: A Case Series
13. Evaluation of clinical effectiveness of MIST ultrasound therapy for the healing of chronic wounds
14. Noncontact ultrasound therapy for adjunctive treatment of nonhealing wounds: retrospective analysis
15. A Prospective, Randomized, Controlled Trial Comparing the Effects of Noncontact, Low-frequency Ultrasound to Standard Care in Healing Venous Leg Ulcers
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